The Infinium OncoArray-500K Kit is the most comprehensive, highest-density BeadChip available for researching cancer predisposition and risk. The Infinium OncoArray-500K contains 500,000 SNPs with a genome-wide backbone of 250,000 tag SNPs. Additional SNPs include genetic variants associated with breast, colorectal, lung, ovarian, and prostate cancers plus SNPs covering ancestry, quantitative traits, pharmacogenetics, and fine-mapping of common cancer susceptibility loci. To support additional research requirements, the Infinium OncoArray-500K can be tailored to incorporate up to 120,000 custom beadtypes*.
The Infinium OncoArray-500K was developed in collaboration with leading experts from the OncoArray consortium†, and draws on many of the features of the successful Collaborative Oncological Gene-environment Study (iCOGS) array1. Designed with candidate SNPs identified by the consortium, the OncoArray provides the most cost-effective means to assess candidate variants potentially associated with cancer risk.
The Infinium OncoArray-500K uses a 24-sample high-throughput screening (HTS) BeadChip to enable maximum throughput, productivity, and genotyping accuracy. Using the proven iScan or HiScan Systems, the Infinium OncoArray-500K is designed to combine affordability with high-density content, providing insight into the relationship between gene variants and cancer predisposition in five of the most prevalent cancers.
* For additional information about custom add-on content, contact your Illumina account manager or sales specialist.
† The OncoArray consortium is an international collaboration of leading experts from the NCI-supported Genetic Association and Mechanisms in Oncology (GAME-ON) consortium, Genome Canada, Genome Quebec, and Cancer Research UK.
|Description||Document Type||File Info|
|Infinium OncoArray-500K BeadChip||Data Sheet||PDF(< 1 MB)|
Catalog IDs: WG-355-1001, WG-355-1002, WG-355-1003, WG-355-1011, WG-355-1012, WG-355-1013