TruSight Hereditary Cancer Panel

Expert-defined content targeting 113 genes associated with genetic cancer risk predisposition.Read More...
选择产品
What products do I need?

TruSight Hereditary Cancer – Enrichment Oligos Only (8 Enrichment Reactions)

20029551

Illumina® DNA Prep with Enrichment, (S) Tagmentation (96 Samples)

20025524

Illumina® DNA Prep with Enrichment, (S) Tagmentation (16 Samples)

20025523

Illumina® DNA Prep, (S) Tagmentation (96 Samples)

20025520

Illumina® DNA Prep, (S) Tagmentation (16 Samples)

20025519

Index Adapters

IDT® for Illumina® DNA/RNA UD Indexes Set A, Tagmentation (96 Indexes, 96 Samples)

20027213

IDT® for Illumina® DNA/RNA UD Indexes Set B, Tagmentation (96 Indexes, 96 Samples)

20027214

IDT® for Illumina Nextera DNA Unique Dual Indexes Set C (96 Indexes, 96 Samples)

20027215

IDT® for Illumina Nextera DNA Unique Dual Indexes Set D (96 Indexes, 96 Samples)

20027216

IDT® for Illumina Nextera DNA Unique Dual Indexes Sets A-D (384 Indexes, 384 Samples)

20027217


Reagents

iSeq 100 i1 Reagent

20021533

iSeq 100 i1 Reagent 4 pack

20021534

MiSeq Reagent Micro Kit v2 (300-cycles)

MS-103-1002

MiSeq Reagent Kit v2 (300-cycles)

MS-102-2002

MiSeq Reagent Kit v3 (600-cycle)

MS-102-3003

MiniSeq Mid Output Kit (300-cycles)

FC-420-1004

MiniSeq High Output Reagent Kit (300-cycles)

FC-420-1003

NextSeq 500/550 Mid Output Kit v2.5 (300 Cycles)

20024905

NextSeq 500/550 High Output Kit v2.5 (300 Cycles)

20024908

配件产品
What accessories do I need?

Flex Lysis Reagent Kit (96 reactions)

20018706

Product Highlights

TruSight Hereditary Cancer Panel的内容根据关键意见领袖对遗传风险评估的反馈意见进行了精心挑选。

  • 包括10,341个探针,靶向113个与癌症体质倾向相关的基因。
  • TruSight Hereditary Cancer Panel包含125个SNP。其中48个是ID SNP,77个是用于多基因风险评分(PRS)的SNP。
  • TruSight Hereditary Cancer Panel与Nextera Flex for Enrichment结合,能让使遗传实验室在6.5小时内制备杂交捕获测序文库,其中的手动操作时间只需大约2小时。
  • 这款panel能适应灵活的工作流程,兼容不同来源的样本,例如基因组DNA、唾液(Oragene试管)和血液(Flex Lysis试剂)。它与所有Illumina台式测序仪兼容,能最大程度地实现2到256个样本批量的灵活性。

TruSight Hereditary Cancer Panel被设计为使用Nextera Flex for Enrichment(NFE)进行文库制备的模块化panel。

可用于多达384个样本的标签可在所有Illumina台式测序仪(iSeq 100、MiSeq、MiniSeq和NextSeq)上实现灵活的批量大小和可扩展性。

Nextera Flex for Enrichment的文库制备工作流程使用基于酶的DNA片段化技术,无需进行机械片段化,从而节约了相关的仪器成本。Nextera Flex for Enrichment已通过了多个自动化系统的认证,可实现用户友好的工作流程。

Frequently Purchased Together

规格

产品比较

TruSight Hereditary Cancer Panel TruSight Cancer癌症相关基因探针集 AmpliSeq for Illumina BRCA Panel
Assay Time ~6.5 hours 1.5 days 5 hours (library prep only; doesn't include library quantification, normalization, or pooling time)
Content Specifications Targets 113 cancer risk-associated genes Fixed set of probes that enrich for 94 genes and 284 SNPs associated with common and rare cancers. Exonic regions and the flanking intronic sequences of the BRCA1 and BRCA2
Hands-On Time 2 hours 5 hours < 1.5 hours
Input Quantity 50 ng 50 ng DNA 1–100 ng (10 ng recommended per pool)
Mechanism of Action Bead-bound transposomes and hybrid-capture chemistry Multiplex PCR
Method Target Enrichment , Targeted DNA Sequencing Target Enrichment , Targeted DNA Sequencing Amplicon Sequencing , Targeted DNA Sequencing
Technology Sequencing Sequencing Sequencing

Method-Specific Workflow Example