TruSight Oncology 500 ctDNA

Assay targeting multiple somatic variant types from plasma, including microsatellite instability (MSI) and tumor mutational burden (TMB). Read More...
Select Product(s)
Library Prep

TruSight Oncology 500 ctDNA Kit (48 samples)

20039252

Price
 
 

TruSight Oncology 500 ctDNA Kit plus Pierian Interpretation Report (16 indexes, 48 Samples)

20043410

Price
 
 

Reagents

NovaSeq 6000 S2 Reagent Kit v1.5 (300 cycles)

20028314

Price
 
 

NovaSeq 6000 S4 Reagent Kit v1.5 (300 cycles)

20028312

Price
 
 

NovaSeq XP 4-Lane Kit v1.5

20043131

Price
 
 

Software and Informatics Options

Illumina DRAGEN Server v3

20040619

Price
 
 

Illumina DRAGEN Server v4

20051343

Price
 
 

ICA Basic Annual Subscription

20044874

ICA Professional Annual Subscription

20044876

ICA Enterprise Annual Subscription

20038994

ICA Enterprise Service and Compliance Add-on (applies to Basic only)

20066830

Illumina Analytics - 1 iCredit

20042038

Price
 
 

Illumina Analytics Starter Package - 1,000 iCredits

20042039

Price
 
 

Illumina Analytics - 5,000 iCredit

20042040

Price
 
 

Illumina Analytics - 50,000 iCredit

20042041

Price
 
 

Illumina Analytics - 100,000 iCredit

20042042

Price
 
 

DRAGEN TruSight Oncology 500 ctDNA Analysis Software, On-Premise, Level 8, 1 Year License

20042107


Services

TruSight Oncology 500 ctDNA training

20045347

Product Highlights

An NGS-based assay that assesses multiple variant types in 523 cancer-related genes from cell-free DNA (cfDNA). Leveraging the power of the NovaSeq 6000 System for high depth of sequencing, unique molecular identifiers (UMIs), and the ultra-rapid Illumina DRAGEN Server v3, provides high sensitivity and specificity to enable comprehensive genomic profiling from cfDNA.

Enable Comprehensive Genomic Profiling in Plasma

  • Same DNA content as TruSight Oncology 500 for detection of single nucleotide variants (SNVs), indels, CNVs, DNA fusions, TMB, and MSI

Achieve Rapid, Accurate Variant Detection

  • Highly sophisticated variant calling algorithm powered and accelerated by DRAGEN

Achieve Confidence in Results

  • Hybrid-capture chemistry, UMIs and high depth of coverage, and sophisticated error correction improve variant calling and reduce artifacts

Leverage the Power of the NovaSeq 6000 System

  • Enable cfDNA analysis with the required depth of sequencing for low-level variant detection in plasma
Learn more about TruSight Oncology 500 Family

TruSight Oncology 500 Product Family

All three assays in the family are designed to identify key biomarkers in guidelines and clinical trials.

TruSight Oncology 500 Assay

Assess key cancer biomarkers from FFPE tumor tissue with the TruSight Oncology 500 Assay.

TruSight Oncology 500 High-Throughput Assay

Batch up to 192 samples at a time while using the same biomarkers and tissue type as the TruSight Oncology 500 assay.

TruSight Oncology 500 ctDNA Assay

Analyze circulating tumor DNA from plasma with the TruSight Oncology 500 ctDNA assay.

Frequently Purchased Together

Specifications

Project Recommendations

Instrument Recommended Number of Samples Read Length
NovaSeq 6000 System 24 samples per run (S4 flow cell), 800M paired-end reads, 35,000x coverage 2 × 150 bp
NovaSeq 6000 System 8 samples per run (S2 flow cell), 800M paired-end reads, 35,000x coverage 2 × 150 bp

Product Comparison

Based on PierianDx Clinical Genomics Knowledgebase, as of March 2020.

Method-Specific Workflow Example

 

Supporting Data and Figures

 

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