NextSeq 1000 and NextSeq 2000 System applications and methods

Flexibility to do more

Fuel a broad range of applications, from targeted panels to whole-genome sequencing and more

NextSeq 2000 P4 reagents

Key applications and methods

Sequencing only the coding regions of the genome enables researchers to focus on the genes most likely to affect phenotype, and offers an accessible combination of turnaround time and price.

Read exome application note

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Library prep
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Sequencing
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Data analysis

mRNA-Seq detects known and novel transcripts and measures transcript abundance for accurate, comprehensive expression profiling.

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Library prep
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Sequencing
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Data analysis

Assess the individual contributions of single cells in complex tissues by profiling the transcriptome.

Read single-cell RNA application note

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Library prep

10x Genomics Chromium Single Cell Gene Expression

This solution provides single-cell transcriptome 3' gene expression and multiomic capabilities to profile tens of thousands of cells. Explore cellular heterogeneity, novel targets, and biomarkers with combined gene expression, surface protein expression, or CRISPR edits in each cell.

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Sequencing
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Data analysis

More applications and methods

Spatial transcriptomics

Detect transcriptional activity to resolve mRNA expression at the cellular level in structurally preserved tissues.

Total RNA sequencing

Analyze coding plus multiple forms of noncoding RNA for a comprehensive picture of the transcriptome.

Immune repertoire analysis

Identify unique receptor variants to map the vast repertoire of immune cells capable of recognizing a seemingly boundless array of targets.

Small whole-genome sequencing

Sequence the entire genome of a bacterium, virus, or other microbe for applications in public health, infectious disease surveillance, molecular epidemiology studies, and environmental metagenomics.

Target enrichment

Use sequence-specific hybridization to analyze genomic regions of interest.

Targeted RNA sequencing

Select and sequence specific transcripts of interest for gene expression profiling studies.

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Hear from fellow researchers

Hear how the NextSeq 2000 System provides scientists with the precision, affordability, and accessibility to make their research a reality. With the help of this system, Zymo Research is delivering cost-effective and timely sequencing services and advancing microbiome research.

NextSeq 2000 System: A range of applications

Learn how the NextSeq 2000 system delivers the flexibility to support your research needs, including bulk RNA-Seq, target enrichment, single-cell RNA-Seq, and much more.