Simple DNA Sequence Analysis Tools
Illumina sequencing systems can produce gigabases of sequencing data per day. Our intuitive bioinformatics solutions help researchers make sense of all those base calls. We offer a wide range of comprehensive and seamless next-generation sequencing (NGS) data analysis solutions, including push-button tools for DNA sequence alignment, variant calling, and data visualization.
Analyze DNA sequencing data from large or small whole genomes, whole exomes, targeted gene regions, and more with our user-friendly software.
Scaling from Exomes to Genomes
The DRAGEN BioIT platform enables GeneDx to scale to whole-genome analysis while keeping costs low, turnaround times short, and accuracy high.
Read InterviewBenefits of DNA Sequencing Data Analysis with Illumina Software Solutions
Data generated on Illumina sequencing instruments can be automatically transferred and stored securely in Illumina Connected Analytics and BaseSpace Sequence Hub. This genomics cloud computing environment features a collection of expert-preferred NGS data analysis apps that support a broad range of studies and simplify NGS data management. These apps provide scalable bioinformatics solutions for analysis of DNA sequencing data and other Illumina data.
The Illumina DRAGEN (Dynamic Read Analysis for GENomics) Bio-IT Platform provides highly accurate, ultra-rapid secondary analysis of NGS data, including data from whole-genome, exome, and targeted DNA sequencing experiments. Available in Illumina Connected Analytics, BaseSpace Sequence Hub, or on-premise, this platform offers a variety of accelerated secondary analysis pipelines, ranging from Germline to Somatic (T/N and Tumor-only), Joint Genotyping, Methylation, a stand-alone map and align pipeline, and more.
In addition, DRAGEN uses lossless genomic compression to rapidly compress and decompress FASTQ files. This technology reduces the data storage footprint by as much as 5x, all while preserving data integrity.
Illumina Connected Analytics and BaseSpace Apps for DNA Sequence Analysis:
- Are accessible to any researcher, regardless of bioinformatics experience
- Support a broad range of applications, including whole-genome, targeted, and exome sequencing data analysis, as well as de novo sequencing, methylation sequencing, metagenomics studies, and more
- Integrate with Illumina sequencing systems
- Present results in easy-to-interpret reports
- Allow instant data sharing with collaborators around the world
| Method | Featured App |
|---|---|
| Whole-Genome Sequencing | DRAGEN
Germline DRAGEN Somatic |
| Tumor-Normal Sequencing | DRAGEN Somatic |
| Exome Sequencing | DRAGEN Enrichment |
| Amplicon Sequencing | BaseSpace DNA Amplicon |
| Methylation Sequencing | DRAGEN Methylation Pipeline |
| 16S rRNA Sequencing | BaseSpace 16S Metagenomics |
View Sample Data Sets
See sample data sets for various methods in BaseSpace Sequence Hub, our genomics cloud computing environment, or test BaseSpace Apps and evaluate results interactively.
Note that a customer login is required to access BaseSpace Sequence Hub and view specific data sets
Interpretation of DNA Sequencing Data
Access powerful turnkey bioinformatics tools that empower you to turn DNA sequencing data and other genomic information into biological insight.
- BaseSpace Correlation Engine: Access a curated library of phenotypic and molecular data to compare and correlate with your DNA sequencing data.
- BaseSpace Variant Interpreter: Quickly identify and classify disease-relevant DNA sequence variants, then communicate findings in a structured report.
- TruSight Software Suite Rare Variant Analysis and Interpretation: Explore research solutions that enable high-throughput labs using whole-genome sequencing to evaluate rare disease-associated variants.
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Additional Resources
Case Study: University of Melbourne Centre for Cancer Research
Using the Illumina Analytics Platform to advance discovery and improve cancer diagnosis and therapy selection.
Illumina DRAGEN Bio-IT Platform Training
Learn more about the accurate, ultra-rapid secondary analysis platform and accompanying pipelines.
Enhance Your Secondary Analysis
The Illumina DRAGEN Bio-IT Platform offers accurate, ultra-rapid secondary analysis for a variety of applications.
BaseSpace Apps for Genome-Scale Analysis
Learn more about apps for common biological applications, including analysis of DNA sequencing data.
Illumina Connected Analytics
A modular, secure data platform for scalable multi-omics data management, analysis, and exploration.
Developer Portal
Access user guides, release notes, and additional technical information.
Illumina Informatics Blog
Keep up with the latest tools and functionality in Illumina’s software and informatics portfolio, with spotlights on useful research methods and data examples.
Genomic Data Storage and Security
Securely store, process, and share large quantities of NGS and other genomic data in the cloud with built-in speed and scalability.