Global genomic data
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BaseSpace Correlation Engine

BaseSpace Correlation Engine applications support early-stage research to identify mechanisms of disease, drug targets, and prognostic or predictive biomarkers. Explore our continually growing library of curated genomic data. Our easy-to-use, web-based tools mine this data and create billions of novel correlations.

Free QuickView and Literature search functionality is available to all users, no login required. Researchers interested in more advanced functionality can subscribe to the full Professional version of BaseSpace Correlation Engine which offers a complete solution for data storage, analysis, and integration. Organizations interested in data sharing and advanced platform features can upgrade to BaseSpace Correlation Engine Enterprise.

Gene Function

  • Analyze gene function across more than 20,000 genomic studies in major disease areas.
  • Assess gene roles across different types of molecular data.
  • Understand gene activity across studies in human, model organisms and cell line models.

Drug and Disease

  • Analyze candidate molecules for pharmacokinetic profiles or toxicity indications.
  • Compare disease profiles across cohorts and different stages of disease. Assess pathways playing significant roles in disease development across multiple studies and data types.


  • Use the cross-species analysis framework to optimize experimental systems to test mechanisms of disease progression or drug response.
  • Compare human data to experimental results from model organisms to understand biological context.

To learn more about BaseSpace Correlation Engine:

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Additional Resources

BaseSpace Correlation Engine is the new name for NextBio Research

Cohort Analysis with BaseSpace Informatics BaseSpace Correlation Engine provides the world’s largest collection of continuously curated genomic knowledge in a secure, HIPAA-compliant, cloud-based environment.

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BaseSpace Correlation Engine Overview Video BaseSpace Correlation Engine enables researchers to aggregate and purify data in the world’s largest secure, cloud-based environment.

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Start Exploring Genomic Data A free 30 day trial of BaseSpace Correlation Engine is instantly available to users with a qualifying educational institution’s email address. Register Now

Request a Free Trial Request a free trial to get full access to the advanced features and capabilities of BaseSpace Correlation Engine. Learn More

Research Method Citation Read the NextBio-authored peer-reviewed publication in PLOS ONE: "Ontology-Based Meta-Analysis of Global Collections of High-Throughput Public Data". Access Article

DNA and Big Data See how biological data mining tools can quickly turn raw sequence data into rich insight. View Video

BaseSpace Cohort Analyzer BaseSpace Cohort Analyzer enables users to apply complex genomic data in novel ways across the entire drug discovery and development process.
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Curated Genomic Data Informs Target Assessment Researchers use BaseSpace Correlation Engine to find gene function and pathway information to support target assessment process.
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