| Feature—Infinium Global Screening Array-24 BeadChip | Description |
|---|---|
| Average scan time per samplea | 1.25 min |
| Average scan time per BeadChip (automated)a | 30 min |
| Maximum weekly throughputa | 5670 samples |
iScan System specifications
A scanner that keeps pace with demand
Delivers high sample throughput and rapid scan times, with no compromises in data quality or coverage levels
iScan System example run
iScan System
a. Approximate values, scan times, and maximum throughput may vary depending on laboratory and system configurations. Scan times based on systems with PCs installed in 2016 or later with LIMS integration turned off.
Weekly throughput of selected Illumina BeadChips with a single iScan System
iScan System
| BeadChip | Approximate scan time per BeadChipa | Maximum sample throughput per weeka |
|---|---|---|
| Infinium Global Screening Array-24 BeadChip | 30 min | 5670 |
| Infinium iSelect HTS-24 BeadChip | 30 min | 5670 |
| Infinium MethylationEPIC-8 BeadChip | 20 min | 3024 |
| Infinium Global Diversity Array-8 BeadChip | 35 min | 1728 |
| Infinium XT iSelect-96 BeadChip | 45 min | 16,128 |
a. Approximate values, scan times, and maximum throughput may vary depending on laboratory and system configurations. Scan times based on systems with PCs installed in 2016 or later with LIMS integration turned off.
Instrument specifications
iScan specifications
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Pixel resolution
0.53 μm
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Laser excitation
532 nm and 658 nm dual-laser excitation
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Image file output
(uncompressed or compressed)TIFF or JPG data file output with automatic image quality analysis
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System dimensions
W × H × D52 cm × 45 cm × 66 cm
(20.5 in × 17.7 in × 26 in) -
Air table dimensions
W × H × D61 cm × 6 cm × 69 cm
(24 in × 2.4 in × 27.2 in) -
Weight
65 kg (143.3 lb)
Key technologies
Bead-based microarray technology
The iScan System uses Illumina microarray technology for a broad range of DNA analysis applications. Each Illumina array, or BeadChip, is covered with hundreds of thousands of copies of specific oligos that act as the capture sequence for specific loci in the genome. When excited by a laser, the nucleotide label emits a signal. The intensity of that signal conveys information about the allelic ratio at that locus.