Understanding Genetic Changes in Cancer
Cancer sequencing using next-generation sequencing (NGS) methods provides more information in less time compared to traditional single-gene and array-based approaches. With NGS, researchers can perform whole-genome studies, targeted gene profiling, tumor-normal comparisons, and more. NGS also offers the sensitivity to detect rare somatic variants, tumor subclones, and circulating DNA fragments.
Key Cancer Sequencing Methods
Cancer Whole-Genome Sequencing
See a comprehensive view of the unique mutations present in tumor tissue.
Learn MoreTargeted Cancer Sequencing
Focus on sequencing a set of genes or genomic regions with known cancer associations.
Learn MoreCancer RNA Sequencing
Identify novel transcripts or determine which genes are overexpressed or underexpressed in tumors.
Learn MoreCirculating Tumor DNA (ctDNA) Sequencing
NGS offers the sensitivity and specificity that researchers need to detect low levels of ctDNA.
Learn MoreFeatured Cancer Sequencing Research
Exploring the Genetic Basis of Oral Cancer
Researchers use various cancer sequencing methods to uncover somatic variants, methylation changes, and other genomic alterations associated with a deadly oral cancer.
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Searching for Cancer Driver Gene Expression Clues
Whole-genome sequencing of ctDNA samples enables researchers to analyze nucleosome patterns and infer the gene expression status of cancer driver genes.
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Deciphering the Role of Long Non-Coding RNA in Cancer
Researchers utilize RNA sequencing to reveal how lncRNAs could be used to identify, measure, and treat cancer.
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New 2023 Methods Guide for Cancer Research
Simple, comprehensive workflows for a broad range of cancer research applications. The new 2023 guide includes: Single-cell sequencing, spatial sequencing, methylation profiling, multiomics, cell-free RNA sequencing and more!
Download Free GuideRecent Cancer Research News & Interviews
Summiting Italy’s Stelvio Pass for cancer research
Illumina employees and the Illumina Corporate Foundation proudly support Stelvio for Life 2023
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Using analytics to improve cancer diagnosis and therapy selection
Developing and automating workflows for analyzing, processing, and sharing genomic data among researchers and clinicians.
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Insights from Dublin: Fostering precision oncology for better patient outcomes
At ECP 2023, Illumina highlights value of comprehensive genomic profiling and integrating biomarkers into practice
Read ArticleSee More Cancer-Specific Content and Products
The user-friendly "Recommended Links" feature allows you to easily find content and products relevant to cancer research and/or a variety of other fields. You can access this option from the top of any illumina.com page.
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Sequencing Limited or Low-Quality Tumor Samples
Find solutions that facilitate analysis of FFPE and limited (needle biopsy or aspirate) tumor DNA.
Detection of Actionable Alterations in Tumors
Wagle et al. demonstrate detection of genomic alterations in tumor samples by high-throughput sequencing.
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Cancer Research Review
An overview of recent cancer research publications featuring Illumina technology.
Cancer and Immune System Research Review
An overview of recent research publications exploring the interaction between tumor cells and the immune system.